What cell-line was used to evaluate cell culture performance with Bioclear™ 11 and how sensitive is it to the degradation product of TBPP?
This question is part of the following Ask The Expert session:
Considerations in Evaluating New Plastic Film for Single-Use Technologies and Film Development
Answered by:
Answer
The improved cell growth performance for Bioclear 11 Cellbag bioreactors was verified by using a CHO DG44 cell line. It showed sensitivity to the bDtBPP degradation product of TBPP at levels as low as down to 0.1 mg/L (100 ppb).