Automated, single-use filtration to increase efficiency in upstream and downstream operations
In examining ways to improve overall bioprocess efficiency, filtration is a step that can sometimes be overlooked. However, it is a key area to improve efficiency, as it is part of both upstream and downstream operations and consumes sizeable resources. The application of single-use technologies coupled with increased automation have successfully improved efficiency in other bioprocess operations, thus it is logical that filtration would also benefit from these technologies. One example of an improved filtration solution is GE Healthcare’s ÄKTA™ readyflux filtration system. The ÄKTA readyflux combines automation and single-use crossflow (tangential flow) filtration and is suitable for pilot and small-scale manufacturing.