Innovative Sorbents Enable a Robust and Streamlined Protein Purification Process
Purification has traditionally been slower to innovate mainly due to the difficulty in changing existing downstream processes, the lack of a universal purification process, and the low capacity of mixed mode chromatography sorbents that has limited their use despite their high resolution. To address these issues, Pall® Biotech recently presented a chromatography process which combines KANEKA KanCapA sorbent, Mustang® Q chromatography membrane and CMM HyperCel™ sorbent. This three-step process has been demonstrated to eliminate the need for diafiltration or dilution between chromatography steps.